3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester CAS NO.27143-07-3

Ethyl [(4-methoxyphenyl) hydrazinyl] chloroacetate is an ester derivative, which is an intermediate for the synthesis of apixaban.

Apixaban is a new oral factor Xa inhibitor developed by Bristol Myers Squibb and Pfizer. It is a new oral anticoagulant drug. By inhibiting an important coagulation factor Xa, apixaban can prevent thrombin formation and thrombosis. Apixaban, developed by bristal Myers Squibb Company, has good bioavailability and high selectivity. It was listed in China in 2013.

Apixaban has good safety and little possibility of drug interaction. There are many ways to eliminate apixaban, which is expected to be used in special people with liver disease or kidney function damage.

COMPANY INTRODUCTION

JIN DUN CHEMICAL belongs to JIN DUN GROUP. It is a professional enterprise dedicated to the development and production of special (meth)acrylate monomers. The head office is located in Shanghai city, near Hongqiao airport.The R&D center of JIN DUN is located in Ningbo city, Zhejiang province.  

JIN DUN CHEMICAL focus on the coating, automobile, electricity and pharmaceutical area, always try best to be the professional supplier of new raw material for the advanced material in coating, automobile chemicals, electricity chemicals and pharmaceutical intermediate.

The EU company of JIN DUN CHEMICAL located at Frankfurt in Germany. It makes us service our customer better in EU, but also takes more valued information for our creation and future developing.

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